Vagus nerve drug may speed gut recovery after pancreatic surgery

NCT ID NCT02425774

First seen Mar 28, 2026 · Last updated May 23, 2026 · Updated 6 times

Summary

This study tested whether giving prucalopride before surgery can reduce inflammation and help the gut start working again sooner after pancreatic tumor removal. The drug aims to mimic electrical stimulation of the vagus nerve, which controls inflammation. The study included 31 adults undergoing partial or full pancreas removal. Researchers measured inflammatory markers and recovery times like passing gas, eating, and bowel movements.

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Contacts and locations

Locations

  • University hospitals Leuven

    Leuven, Vlaams-Brabant, 3000, Belgium

Conditions

Explore the condition pages connected to this study.