New pain combo aims to get bowels moving faster after surgery

NCT ID NCT07651722

Recruiting now Symptom relief Sponsor: Tianjin First Central Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of a long-lasting numbing drug (liposomal bupivacaine) injected into the belly wall plus a special painkiller (oxycodone) given through an IV can help the gut recover faster after major abdominal surgery. 132 adults having small bowel or colorectal surgery will be randomly assigned to one of three pain treatment groups. The main goal is to see if this combo improves bowel function in the first week after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: liposomal bupivacaine and oxycodone
What this could lead to: If it works, this could lead to a standard pain management plan that helps patients recover bowel function faster after abdominal surgery.
What could go wrong: This is a small, early-phase trial at one hospital, so results may not apply to everyone. The new drug combo may not work better than current options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative paralytic ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE ILEUS POSTOPERATIVE PAIN

Contacts and locations

Locations

Tianjin First Central Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300384, China

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