New pain combo aims to get bowels moving faster after surgery

NCT ID NCT07651722

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of a long-lasting numbing drug (liposomal bupivacaine) injected into the belly wall plus a special painkiller (oxycodone) given through an IV can help the gut recover faster after major abdominal surgery. 132 adults having small bowel or colorectal surgery will be randomly assigned to one of three pain treatment groups. The main goal is to see if this combo improves bowel function in the first week after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liposomal bupivacaine and oxycodone

What this could lead to

If it works, this could lead to a standard pain management plan that helps patients recover bowel function faster after abdominal surgery.

What could go wrong

This is a small, early-phase trial at one hospital, so results may not apply to everyone. The new drug combo may not work better than current options.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative paralytic ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Tianjin First Central Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300384, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••