New hope for Hard-to-Treat cancers: experimental drug PRTH-101 enters human testing
NCT ID NCT05753722
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 30 times
Summary
This early-phase study tests a new drug called PRTH-101, alone or with an approved immunotherapy (pembrolizumab), in adults with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see if the drug shrinks tumors. About 270 participants will take part.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NON SMALL CELL LUNG CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Honor Health Research Institute
RECRUITINGScottsdale, Arizona, 85258, United States
Contact
Contact
-
Mass General Cancer Center
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact
-
NEXT Houston
RECRUITINGHouston, Texas, 77054, United States
Contact
Contact
-
NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact
Contact
-
Next Oncology
RECRUITINGIrving, Texas, 75039, United States
Contact
Contact
-
Next Oncology
RECRUITINGFairfax, Virginia, 22031, United States
Contact
Contact
-
Providence Cancer Institute Franz Clinic
RECRUITINGPortland, Oregon, 97213, United States
Contact
Contact
-
The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact
-
University of Pittsburgh Medical Center Hillman Cancer Center
COMPLETEDPittsburgh, Pennsylvania, 15232, United States
-
Vanderbilt-Ingram Cancer Center
RECRUITINGNashville, Tennessee, 27232, United States
Contact
Contact
-
Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06511, United States
Contact
Contact
Conditions
Explore the condition pages connected to this study.