Could a simple injection ease your back pain for good?

NCT ID NCT03712527

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This study tests whether a single injection of platelet-rich plasma (PRP) into a damaged spinal disc can reduce pain and improve daily function in people with chronic low back pain. About 126 adults aged 18 to 60 with a specific type of disc inflammation (Modic 1) will receive either PRP or a placebo. The main goal is to see if at least 30% more people feel meaningful improvement after 3 months.

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Contacts and locations

Locations

  • APHP Cochin

    Paris, France

  • CHU Bordeaux

    Bordeaux, France

  • CHU Nice

    Nice, France

  • CHU Nîmes

    Nîmes, France

  • CHU Toulouse

    Toulouse, France

  • Univesity Hospital od Montpellier

    Montpellier, 34295, France

Conditions

Explore the condition pages connected to this study.