Could a blood injection make prolapse surgery more durable?
NCT ID NCT05731284
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This trial tests whether injecting platelet-rich plasma (PRP) into vaginal tissue during prolapse surgery helps improve healing and surgical outcomes. PRP is made from a patient's own blood and contains growth factors that may aid tissue repair. The study compares PRP to a placebo (saline) in 60 women undergoing native tissue prolapse repair, measuring pelvic support and safety over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Platelet-rich plasma (PRP)
- What this could lead to
- If it works, PRP could become a standard addition to prolapse surgery, helping tissues heal better and reducing the chance of prolapse returning.
- What could go wrong
- This is a small, early-stage trial with 60 participants, so results may not apply to everyone. PRP is generally safe, but there is a small risk of infection or no benefit over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PELVIC ORGAN PROLAPSE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Phone call before a bladder test may ease anxiety and improve results
- Silicone splint aims to prevent prolapse from returning after surgery
- Tiny bacteria, big impact: could vaginal microbes determine surgical success?
- Tiny trial on preventive bladder sling halted early — no clear answers
- Robot vs. vaginal surgery for prolapse: which is better? trial stopped early.
- New chair therapy vs. traditional exercises for pelvic support