Could a blood injection make prolapse surgery more durable?

NCT ID NCT05731284

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial tests whether injecting platelet-rich plasma (PRP) into vaginal tissue during prolapse surgery helps improve healing and surgical outcomes. PRP is made from a patient's own blood and contains growth factors that may aid tissue repair. The study compares PRP to a placebo (saline) in 60 women undergoing native tissue prolapse repair, measuring pelvic support and safety over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Platelet-rich plasma (PRP)
What this could lead to
If it works, PRP could become a standard addition to prolapse surgery, helping tissues heal better and reducing the chance of prolapse returning.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. PRP is generally safe, but there is a small risk of infection or no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

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