Proton beam therapy tested for liver cancer – early results show promise and risks

NCT ID NCT04805788

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tested a precise type of radiation called proton beam therapy in 9 people with liver cancer. The goal was to see if it could control the cancer while limiting damage to the liver. The study was stopped early, so the findings are limited, but early data suggest it may be a useful option for some patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton beam radiotherapy

What this could lead to

If successful, this could show that proton radiotherapy is a safe and effective way to treat liver cancer with fewer side effects than standard radiation.

What could go wrong

This was a very small, early-phase trial that was terminated early, so results are limited. Proton therapy may still cause liver damage or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States