Massive 75,000-Patient registry aims to unlock best uses of proton therapy

NCT ID NCT02436941

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Loma Linda University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This registry follows up to 75,000 cancer patients treated with proton or standard X-ray radiation at Loma Linda University Medical Center, some since 1990. The goal is to track long-term outcomes like disease-free survival and local recurrence to learn which radiation approaches work best for different cancers. Participants must have a diagnosis treatable by radiation and provide consent.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proton or photon radiation therapy
What this could lead to: If successful, this registry could help doctors understand which types of radiation work best for different cancers, improving future treatment decisions.
What could go wrong: This is an observational registry, not a treatment trial. It collects data from past and current patients, so it cannot prove new treatments or directly benefit participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign neoplasm cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER

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