New hope for advanced prostate cancer: radioactive drug added to chemo in major trial

NCT ID NCT03574571

Ongoing Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing if adding a radioactive drug called Radium-223 to standard chemotherapy (docetaxel) helps men with advanced prostate cancer that has spread to the bones live longer. The study enrolled 732 men to directly compare the combination treatment against chemotherapy alone. The main goal is to see if the combined approach improves overall survival for patients with this serious form of cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Amphia Hospital

Breda, 4818, Netherlands
Atrium Health/ Levine Cancer Institute

Monroe, North Carolina, 28112, United States
Banner MD Anderson Cancer Center

Gilbert, Arizona, 85234, United States
Beneficência Portuguesa

São Paulo, Brazil
Boca Raton Regional Hospital

Boca Raton, Florida, 33486, United States
Bronx VA Hospital

New York, New York, 10468, United States
CPORS - Centro de Pesquisa em Oncologia do Hospital São Lucas da PUCRS

Porto Alegre, 90610000, Brazil
Canisius Wilhelmina Ziekenhuis (CWZ)

Nijmegen, 6532, Netherlands
Centro de Pesquisas São Lucas - Sociedade Campineira de Educação e Instrução (SCEI)

São Paulo, Brazil
Clinic de Barcelona

Barcelona, 08036, Spain
Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, 89128, United States
Dayton Physicians Network

Kettering, Ohio, 45409, United States
Deventer Ziekenhuis

Deventer, Netherlands
Erasmus MC Cancer Institute

Rotterdam, 3015 GD, Netherlands
Franciscus Gasthuis & Vlietland

Rotterdam, 3045, Netherlands
Haaglanden Medical Center

The Hague, 2512, Netherlands
Helen Graham Cancer Center (Christiana Care)

Newark, Delaware, 19713, United States
Hospital Del Mar

Barcelona, 08003, Spain
Hospital Erasto Gaertner

Curitiba, Brazil
Hospital Israelita Albert Einstein

São Paulo, 05652-900, Brazil
Hospital Moinhos de Vento (HMV)

Porto Alegre, Brazil
Hospital Provincial de Castellón

Castellon, 12006, Spain
Hospital Sírio Libanês

Brasília, 70200-730, Brazil
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Central de Asturias (HUCA)

Oviedo, Avenida de Roma S/n, 33011, Spain
Hospital Universitario Virgen Del Rocío

Seville, Spain
Hospital de Amor de Barretos (Fundação Pio XII) / Barretos Cancer Hospital

Barretos, Dr. Paulo Prata, 14784-400, Brazil
Houston Methodist Research Institute

Houston, Texas, 77030, United States
Indiana University

Indianapolis, Indiana, 46202, United States
Instituto Brasileiro de Controle do Câncer/IBCC

São Paulo, State of São Paulo, Brazil
Instituto Valenciano de Oncología

Valencia, Spain
Instituto de Medicina Integral Professor Fernando Figueira (IMIP)

Boa Vista, Pernambuco, 50.070-902, Brazil
Isala Kliniek

Zwolle, 8025, Netherlands
MD Anderson Cancer Center at Cooper

Camden, New Jersey, 08103, United States
Maasstad Hospital

Rotterdam, 3079, Netherlands
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
MidLantic Urology

Bala-Cynwyd, Pennsylvania, 19004, United States
Millennium Physicians

Houston, Texas, 77090, United States
Mount Sinai Medical Center (Miami)

Miami, Florida, 33140, United States
Nebraska Cancer Specialists

Omaha, Nebraska, 68114, United States
Nederlands Kanker Instituut

Amsterdam, Plesmanlaan, 1066 CX, Netherlands
New Jersey Urology

Saddle Brook, New Jersey, 07663, United States
New Mexico Oncology and Hematology

Albuquerque, New Mexico, 87109, United States
New York Presbyterian Hospital-Weill Medical College of Cornell University

New York, New York, 10065, United States
Noordwest Ziekenhuisgrouep Alkmaar (NWZ)

Alkmaar, 1815, Netherlands
Ochsner Cancer Institute

New Orleans, Louisiana, 70121, United States
Ramón y Cajal Hospital

Madrid, Madrid, 28034, Spain
Roswell Park Cancer Institute

Buffalo, New York, 14263-0001, United States
Rush University Medical Center

Chicago, Illinois, 606012, United States
St. Antonius Ziekenhuis (Utrecht)

Utrecht, Netherlands
Tergooi Hospital

Hilversum, 1213, Netherlands
University of Buffalo

Buffalo, New York, 14203, United States
University of Cincinnati Medical Center

Cincinnati, Ohio, 45219, United States
University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
University of Massachusetts

Worcester, Massachusetts, 01655, United States
University of Michigan Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of North Carolina

Chapel Hill, North Carolina, 27514, United States
University of Oklahoma

Oklahoma City, Oklahoma, 73104, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
University of Washington

Seattle, Washington, 98109, United States
Vall d'Hebron Institute of Oncology (VHIO)

Barcelona, 08035, Spain
XCancer Omaha / Urology Cancer Center

Omaha, Nebraska, 68130, United States
Yale University- Yale Cancer Center

New Haven, Connecticut, 06510, United States
Ziekenhuisgroep Twente (ZGT)

Almelo, 7609, Netherlands

Conditions

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PROSTATE CANCER