Zapping prostate cancer with guided radiation and supercharged immunity

NCT ID NCT04946370

Summary

This study is for men with advanced prostate cancer that has spread and stopped responding to standard hormone-blocking treatments. Researchers are testing if adding a new, targeted radiation drug (225Ac-J591) to a standard immunotherapy (pembrolizumab) and hormone therapy works better than the immunotherapy and hormone therapy alone. The radiation drug is designed to seek out and deliver a powerful dose directly to prostate cancer cells throughout the body.

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Contacts and locations

Locations

  • Columbia University Irving Cancer Center

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • New York Presbyterian/Brooklyn Methodist Hospital

    Brooklyn, New York, 11215, United States

  • New York Presbyterian/Weill Cornell Medical Center

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.