Hormone-Plus-Radiation combo shows promise against aggressive prostate cancer

NCT ID NCT02772588

First seen Feb 01, 2026 · Last updated May 08, 2026 · Updated 14 times

Summary

This study tested whether giving anti-testosterone medications before, during, and after high-dose, targeted radiation can prevent prostate cancer from returning in men with very high-risk disease. Sixty-four participants received the combination treatment. The main goal was to see how many men had a rise in PSA (a cancer marker) after treatment, which would signal the cancer had come back.

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Contacts and locations

Locations

  • John Hopkins Medical Center

    Baltimore, Maryland, 21287, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Rockville

    Rockville Centre, New York, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • Weill Cornell Medical Center

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.