New hope for High-Risk prostate cancer: drug combo aims to block deadly spread

NCT ID NCT04484818

Ongoing Disease control Sponsor: ECOG-ACRIN Cancer Research Group Source: ClinicalTrials.gov ↗

Summary

This study is for men with high-risk prostate cancer who have had surgery to remove the prostate. It tests whether adding a new drug called darolutamide to standard hormone-blocking therapy is better at preventing the cancer from spreading to other parts of the body. The goal is to see if this combination helps men live longer without their cancer returning or spreading, compared to hormone therapy alone.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Addison Gilbert Hospital

Gloucester, Massachusetts, 01930, United States
Audie L Murphy VA Hospital

San Antonio, Texas, 78229, United States
Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Beverly Hospital

Beverly, Massachusetts, 01915, United States
Bozeman Deaconess Hospital

Bozeman, Montana, 59715, United States
Broadlawns Medical Center

Des Moines, Iowa, 50314, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle on Vermilion

Danville, Illinois, 61832, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
City of Hope South Pasadena

South Pasadena, California, 91030, United States
City of Hope Upland

Upland, California, 91786, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Edward Hospital/Cancer Center

Naperville, Illinois, 60540, United States
Elmhurst Memorial Hospital

Elmhurst, Illinois, 60126, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
GenesisCare USA - Clarkston

Clarkston, Michigan, 48346, United States
GenesisCare USA - Farmington Hills

Farmington Hills, Michigan, 48334, United States
GenesisCare USA - Lakewood Ranch

Lakewood Rch, Florida, 34202, United States
GenesisCare USA - Macomb

Macomb, Michigan, 48044, United States
GenesisCare USA - Madison Heights

Madison Heights, Michigan, 48071, United States
GenesisCare USA - Plantation

Plantation, Florida, 33324, United States
GenesisCare USA - Troy

Troy, Michigan, 48098, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813, United States
Illinois CancerCare - Washington

Washington, Illinois, 61571, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States
Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805, United States
Lahey Medical Center-Peabody

Peabody, Massachusetts, 01960, United States
Los Angeles County-USC Medical Center

Los Angeles, California, 90033, United States
Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Medical Oncology and Hematology Associates-Des Moines

Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates-West Des Moines

Clive, Iowa, 50325, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Medical Center

Springfield, Illinois, 62781, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Mission Cancer and Blood - Laurel

Des Moines, Iowa, 50314, United States
Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
New Hampshire Oncology Hematology PA-Concord

Concord, New Hampshire, 03301, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern University

Chicago, Illinois, 60611, United States
Pali Momi Medical Center

‘Aiea, Hawaii, 96701, United States
Parkland Memorial Hospital

Dallas, Texas, 75235, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Queen's Cancer Cenrer - POB I

Honolulu, Hawaii, 96813, United States
Queen's Cancer Center - Kuakini

Honolulu, Hawaii, 96817, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Ralph H Johnson VA Medical Center

Charleston, South Carolina, 29401, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Rush - Copley Medical Center

Aurora, Illinois, 60504, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Broadway Medical Center

Fargo, North Dakota, 58122, United States
Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States
Solinsky Center for Cancer Care

Manchester, New Hampshire, 03103, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
Straub Clinic and Hospital

Honolulu, Hawaii, 96813, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern Clinical Center at Richardson/Plano

Richardson, Texas, 75080, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
UT Southwestern/Simmons Cancer Center-Fort Worth

Fort Worth, Texas, 76104, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Toledo

Toledo, Ohio, 43614, United States
University of Wisconsin Carbone Cancer Center

Madison, Wisconsin, 53792, United States
VA Palo Alto Health Care System

Palo Alto, California, 94304, United States
Virginia Commonwealth University/Massey Cancer Center

Richmond, Virginia, 23298, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Wake Forest University at Clemmons

Clemmons, North Carolina, 27012, United States
William Beaumont Hospital - Troy

Troy, Michigan, 48085, United States
William Beaumont Hospital-Royal Oak

Royal Oak, Michigan, 48073, United States
William S Middleton VA Medical Center

Madison, Wisconsin, 53705, United States
Winchester Hospital

Winchester, Massachusetts, 01890, United States

Conditions

Explore the condition pages connected to this study.

PROSTATE CARCINOMA