New combo therapy aims to halt prostate cancer spread in high-risk patients

NCT ID NCT07237269

First seen Nov 19, 2025 · Last updated May 13, 2026 · Updated 24 times

Summary

This study is for men with prostate cancer that has spread to pelvic lymph nodes only detectable by a special PSMA-PET scan. It compares standard hormone therapy plus radiation to a stronger combination that includes abiraterone and prednisone. The goal is to see if the stronger therapy improves survival without cancer progression over 5 years. About 140 participants will be randomly assigned to one of the two treatment groups.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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