Could fewer radiation sessions be just as safe for prostate cancer?

NCT ID NCT05820633

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 30 times

Summary

This study compares a new, ultra-short radiation schedule (5 treatments) against the standard longer course for prostate cancer that has spread to lymph nodes. About 500 men will receive either the short or standard radiation, plus a brachytherapy boost and hormone therapy. The goal is to see if the shorter schedule causes fewer side effects while still controlling the cancer.

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Contacts and locations

Locations

  • BC Cancer Sindi Ahluwalia centre for the Southern Interior

    Kelowna, British Columbia, V1Y 5L3, Canada

  • CHU de Québec - Université Laval

    Québec, G1R 2J6, Canada

  • CISSS de Laval, Hôpital de la Cité-de-la-Santé

    Laval, Quebec, H7M 3L9, Canada

  • CISSS de l'Outaouais, Hôpital de Gatineau

    Gatineau, Quebec, J8P 7H2, Canada

  • CISSS de la Montérégie-Centre, Hôpital Charles-Le Moyne

    Longueuil, Quebec, J4V 2H1, Canada

  • CIUSSS de l'Est-de-l'Île-de-Montréal, Hôpital Maisonneuve-Rosemont

    Montreal East, Quebec, H1T 2M4, Canada

  • CIUSSS de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke (CHUS)

    Sherbrooke, Quebec, Canada

  • CIUSSS du Centre-Ouest-de-l'Île-de-Montréal, Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

  • Carlo Fidani Peel Regional Cancer Centre

    Mississauga, Ontario, L5M 2N1, Canada

  • Cedars Cancer Centre, McGill University Health Centre (MUHC)

    Montreal, Quebec, H4A 3J1, Canada

  • Lakeridge Health Oshawa Cancer centre

    Oshawa, Ontario, L1G 2B9, Canada

Conditions

Explore the condition pages connected to this study.