Targeted drug combo aims to halt advanced prostate cancer in select patients

NCT ID NCT05689021

Summary

This study is testing a combination of two drugs, niraparib/abiraterone and prednisone, in men with advanced prostate cancer that has spread and has stopped responding to standard hormone-blocking treatments. The treatment is specifically for patients whose cancer has a particular genetic change called a SPOP mutation. The main goal is to see if this combination can significantly lower a key cancer marker (PSA) and control the cancer's growth for a longer period.

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Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.