Early trial tests new drug duo for Tough-to-Treat prostate cancer

NCT ID NCT05999968

Summary

This small, early-stage study aimed to check the safety and side effects of combining two drugs, abemaciclib and darolutamide, for men with advanced prostate cancer that had spread and stopped responding to standard hormone therapy. It involved 10 participants and looked at how well the body handled the drug combination. The main goal was to see if the two drugs could be given together safely, not to prove they were highly effective.

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Contacts and locations

Locations

  • Highlands Oncology Group

    Springdale, Arkansas, 72762, United States

  • Hospital General Universitario Gregorio Marañon

    Madrid, Madrid, Comunidad de, 28009, Spain

  • Hospital Infanta Cristina

    Badajoz, 06006, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, Comunidad de, 28041, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, Madrid, Comunidad de, 28034, Spain

  • Hospital Universitario Virgen Del Rocio

    Seville, 41013, Spain

  • Instituto Catalan de Oncologia - Hospital Duran i Reynals

    L'Hospitalet de Llobregat, Catalunya [Cataluña], 8907, Spain

  • Klinikum Rechts Der Isar Der Technischen Universität München

    Munich, Bavaria, 81675, Germany

  • Laura and Isaac Perlmutter Cancer Center

    New York, New York, 10016, United States

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Studienpraxis Urologie

    Nürtingen, Baden-Wurttemberg, 72622, Germany

  • Universitaetsklinikum Hamburg-Eppendorf

    Hamburg, 20246, Germany

  • Universitätsklinikum Schleswig-Holstein

    Lübeck, Schleswig-Holstein, 23538, Germany

Conditions

Explore the condition pages connected to this study.