Triple-Drug attack before surgery aims to wipe out High-Risk prostate cancer

NCT ID NCT07027124

First seen Mar 22, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests whether giving a mix of hormone therapy (ADT), a targeted drug (darolutamide), and an immunotherapy (pembrolizumab) before prostate removal surgery, followed by more immunotherapy after surgery, can reduce or eliminate cancer in high-risk prostate cancer patients. About 40 men with aggressive, non-spread prostate cancer will take part. The goal is to see if this approach leads to very little or no cancer left at the time of surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10028, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.