Radiation 'Bullet' added to standard drug in major prostate cancer fight

NCT ID NCT02194842

Ongoing Disease control Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing if combining a standard hormone-blocking pill (enzalutamide) with a bone-targeted radiation treatment (Ra223) works better than the pill alone for men whose prostate cancer has spread to their bones and is no longer responding to standard hormone therapy. The main goal is to see if the combination can keep the cancer from getting worse for a longer time, delay bone pain, and help patients live longer. It is for men with few or no symptoms from their cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AZ Groeninge Kortrijk

Kortrijk, Belgium
AZ Turnhout

Turnhout, Belgium
Assistance Publique - Hopitaux de Paris - CHU Henri Mondor

Créteil, 94000, France
CHU Dinant Godinne - UCL Namur

Yvoir, 5530, Belgium
CHUM - Centre Hospitalier de l'Université de Montreal - Pavillon Saint-Luc

Montreal, Quebec, H2X 3J4, Canada
Centre Francois Baclesse

Caen, 14076, France
Centre Leon Berard

Lyon, 69008, France
Centre de sante et de services sociaux de Chicoutimi

Chicoutimi, Quebec, G7H 5H6, Canada
Centro Pesquisas Oncologicas

Florianópolis, 88034000, Brazil
Centro de Estudos e Pesquisa Hematologia e Oncologia

Santo André, 09060-650, Brazil
Centro de Pesquisas Clinicas em Oncologia - Hospital Sao Lucas

Porto Alegre, 90610 000, Brazil
Centro de Tratamentos de Tumores Botafogo

Rio de Janeiro, 22250-040, Brazil
Chuq-Pavillon Hotel-Dieu De Quebec

Québec, Quebec, G1R 2J6, Canada
Cliniques Universitaires Saint-Luc

Brussels, 1200, Belgium
Clínica Oncológica - CLION

Salvador, 41810-570, Brazil
Complejo Hospitalario de Navarra

Pamplona, 31008, Spain
Cork University Hospital

Cork, TI2DC4A, Ireland
Corporacio Sanitaria Parc Tauli

Sabadell, Spain
Gustave Roussy

Villejuif, 94805, France
Hamilton And District Urology Association

Hamilton, Ontario, L8N 1T8, Canada
Hopital Universitaire Brugmann

Brussels, 1020, Belgium
Hopitaux Universitaires Bordet-Erasme - Hopital Universitaire Erasme

Brussels, 1070, Belgium
Hopitaux Universitaires de Strasbourg - Hôpitaux Universitaires de Strasbourg - Hôpital civil

Strasbourg, 67091, France
Hospital Beneficencia Portuguesa

São Paulo, 01321-000, Brazil
Hospital Clinic Universitari de Barcelona

Barcelona, 08036, Spain
Hospital De La Santa Creu I Sant Pau

Barcelona, 08041, Spain
Hospital Del Mar

Barcelona, 08003, Spain
Hospital Erasto Gaertner

Curitiba, 81520-060, Brazil
Hospital Moinhos de Vento

Porto Alegre, 90035-001, Brazil
Hospital Paulistano

São Paulo, 01321-001, Brazil
Hospital Universitario QuironSalud

Madrid, 28223, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28034, Spain
Hospital Universitario de La Princesa

Madrid, 28006, Spain
Hospital Universitario de Salamanca

Salamanca, 37007, Spain
Hospital de Amor

Barretos, 14.784-400, Brazil
Institut de Cancerologie de l'Ouest (ICO) - Centre Paul Papin

Angers, 49055, France
Institut de Cancerologie de l'Ouest (ICO) - Centre Rene Gauducheau

Saint-Herblain, 44805, France
Institut régional du Cancer Montpellier

Montpellier, 34298, France
Instituto de Medicina Integral Professor Fernando Figueira - IMIP

Recife, 50070-550, Brazil
Istituto Europeo di Oncologia

Milan, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

Meldola, Italy
Kantonsspital St Gallen

Sankt Gallen, Switzerland
London Regional Cancer Center

London, Ontario, N6A 4L6, Canada
Maria Sklodowska-Curie Memorial Cancer Centre

Warsaw, Poland
Nottingham University Hospitals NHS Trust - City Hospital

Nottingham, United Kingdom
Odette Cancer Centre - Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
Oncocentro

Fortaleza, 60130-241, Brazil
Oncology Institute of Southern Switzerland - Ospedale San Giovanni

Bellinzona, 6500, Switzerland
Ospedale B.Ramazzini

Carpi, 41012, Italy
Rigshospitalet

Copenhagen, Denmark
Royal Marsden Hospital - Chelsea, London

London, SW3 6JJ, United Kingdom
Saint John Regional Hospital

Saint John, New Brunswick, E2L 4, Canada
Sao Camilo Oncologia - Instituto Brasileiro de Controle do Cancer

São Paulo, 03.102-002, Brazil
Soerlandet Sykehus-Kristiansand

Kristiansand, 4604, Norway
St. Vincent's University Hospital

Dublin, Ireland
Tallaght University Hospital

Dublin, Ireland
The Christie NHS Foundation Trust

Manchester, United Kingdom
U.Z. Leuven - Campus Gasthuisberg

Leuven, 3000, Belgium
United Lincolnshire Hospitals NHS Trust - Lincoln County Hospital

Lincoln, LN2 5QY, United Kingdom
UniversitaetsSpital Zurich

Zurich, 8091, Switzerland
Universitair Ziekenhuis Antwerpen

Edegem, 2650, Belgium
University Health Network - Oci Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University Hospital of North Norway

Tromsø, N-9038, Norway
Vall d'Hebron Institut d'Oncologia

Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.

PROSTATE CANCER