Bee product may soothe radiation mouth sores in cancer patients

NCT ID NCT07597525

Completed Symptom relief Sponsor: Ankara Oncology Research and Training Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a propolis mouth rinse could delay or prevent severe oral mucositis (painful mouth sores) in 140 head and neck cancer patients undergoing radiation. Participants used either a 15% propolis solution or a placebo four times daily alongside standard oral care. The goal was to see if propolis could reduce this common, painful side effect and improve treatment tolerance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 15% propolis solution
What this could lead to: If it works, this could offer a natural, low-cost way to delay or prevent severe mouth sores during radiation therapy, improving quality of life for head and neck cancer patients.
What could go wrong: This is a small, completed trial with 140 participants. The benefit may be modest or not apply to all patients. Allergic reactions to bee products are a risk.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL MUCOSITIS IN HEAD AND NECK CANCER

Contacts and locations

Locations

Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Ankara, Ankara, 06200, Turkey (Türkiye)

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