Brain surgery sedation: do current dosing models work in the ICU?
NCT ID NCT06584097
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks whether computer models that help doctors dose the sedatives propofol and remifentanil during brain surgery also work well when patients are in the intensive care unit afterward. Researchers will compare how accurate the models are in the ICU versus during surgery. The goal is to see if these models can be used to guide sedation after surgery, potentially improving patient comfort and safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- propofol and remifentanil
- What this could lead to
- If successful, this could improve how doctors dose these sedatives in the ICU after brain surgery, making care safer and more personalized.
- What could go wrong
- This is a small, early-stage study with only 42 participants, so results may not apply to all patients. It measures drug levels, not direct patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NEUROSURGICAL PATIENTS are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fondazione IRCCS Istituto Neurologico C. Besta
RECRUITINGMilan, Milano, 20133, Italy
-
Foundation IRCCS Carlo Besta Neurological Institute
RECRUITINGMilan, Italy, 20133, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.