Sleep drug shows promise for treating depression in seniors

NCT ID NCT06867549

Recruiting now Symptom relief Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a low or moderate dose of propofol, a sleep-inducing drug, combined with brief behavioral therapy for insomnia, can improve sleep and depression symptoms in adults aged 60 and older with treatment-resistant depression. Seventy participants will receive two propofol infusions and several therapy sessions. The goal is to see if boosting deep sleep can help ease depression.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Washington University School of Medicine/Barnes-Jewish Hospital
RECRUITING

St Louis, Missouri, 63110, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••