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Could a vacuum dressing slash infection rates after major abdominal surgery?

NCT ID NCT05977816

Ongoing Disease control Sponsor: Royal College of Surgeons, Ireland Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This trial tests whether a negative pressure wound therapy (NPWT) dressing — a special vacuum-sealed bandage — can reduce surgical site infections and improve scar appearance compared to a standard dressing in people who have had a midline laparotomy (a large abdominal incision). About 2,000 adults undergoing this type of surgery will be randomly assigned to receive either the NPWT dressing or a standard dressing after their operation. Researchers will track infection rates for up to six months and also measure quality of life and scar healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Negative Pressure Wound Therapy (NPWT) dressing applied to the wound after surgery
What this could lead to
If it works, this could establish NPWT as a better way to prevent surgical site infections and improve scar healing after abdominal surgery.
What could go wrong
This is a single trial, and results may not apply to all types of abdominal surgery. NPWT dressings can be more expensive and may cause skin irritation in some patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

injury Surgical Wound Surgical Wound Infection Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COSMESIS WOUND INFECTION WOUND SURGICAL

Contacts and locations

Locations

  • Beaumont Hospital

    Dublin, Ireland

  • Letterkenny University Hospital

    Letterkenny, Ireland

  • Mater Misericordiae University Hospital

    Dublin, Ireland

  • Mayo University Hospital

    Castlebar, Ireland

  • Sligo University Hospital

    Sligo, Ireland

  • St James's Hospital

    Dublin, Ireland

  • Tallaght University Hospital

    Dublin, Ireland

  • University Hospital Galway

    Galway, Ireland

  • University Hospital Limerick

    Limerick, Ireland

  • University Hospital Waterford

    Waterford, Ireland

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