New hope for saving limbs: rerouting blood flow could prevent amputation

NCT ID NCT05313165

First seen Apr 20, 2026 · Last updated May 10, 2026 · Updated 4 times

Summary

This study tests a new procedure that reroutes blood flow through a vein instead of a blocked artery to save the leg from amputation. It is for people with severe, late-stage limb-threatening ischemia who have ulcers or gangrene. The main goal is to see if the procedure helps people keep their leg and survive.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ascension Columbia St. Mary's Hospital

    WITHDRAWN

    Milwaukee, Wisconsin, 53211, United States

  • Atrium Health

    COMPLETED

    Charlotte, North Carolina, 28204, United States

  • Boston Medical Center

    WITHDRAWN

    Boston, Massachusetts, 02118, United States

  • Cornell University

    COMPLETED

    New York, New York, 10065, United States

  • Dartmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03766, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Holy Name Medical Center

    COMPLETED

    Teaneck, New Jersey, 07666, United States

  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

    COMPLETED

    Torrance, California, 90502, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mount Sinai

    COMPLETED

    New York, New York, 10029, United States

  • NYU Langone Health

    COMPLETED

    New York, New York, 10016, United States

  • Northwell Health Long Island Jewish Medical Center

    RECRUITING

    Lake Success, New York, 11042, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Penn State Health

    COMPLETED

    Hershey, Pennsylvania, 17033, United States

  • Presbyterian Healthcare

    COMPLETED

    Albuquerque, New Mexico, 87113, United States

  • Rush University Medical Center

    COMPLETED

    Chicago, Illinois, 60612, United States

  • Sentara Norfolk General Hospital

    RECRUITING

    Norfolk, Virginia, 23507, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University School of Medicine

    COMPLETED

    Palo Alto, California, 94304, United States

  • Tallahassee Research Institute

    WITHDRAWN

    Tallahassee, Florida, 32308, United States

  • The Cardiac and Vascular Institute

    RECRUITING

    Gainesville, Florida, 32605, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Medical College of Wisconsin

    WITHDRAWN

    Milwaukee, Wisconsin, 53226, United States

  • UCSF

    COMPLETED

    San Francisco, California, 94143, United States

  • UMass Chan Medical School

    COMPLETED

    Worcester, Massachusetts, 01655, United States

  • UT Southwestern Medical Center

    COMPLETED

    Dallas, Texas, 75390, United States

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, San Diego Health

    WITHDRAWN

    La Jolla, California, 92093, United States

  • University of Florida

    COMPLETED

    Gainesville, Florida, 32608, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Vascular Institute of Atlantic Medical Imaging

    COMPLETED

    Pomona, New Jersey, 08240, United States

  • Washington University / Barnes Jewish

    WITHDRAWN

    St Louis, Missouri, 63110, United States

  • Yale University

    COMPLETED

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.