Probiotics may shield cancer patients from Immunotherapy's gut woes

NCT ID NCT06508034

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking an over-the-counter probiotic (VSL#3® 450B) can prevent colitis (colon inflammation) and diarrhea in cancer patients receiving immunotherapy. Up to 45% of patients on these drugs develop this side effect. The trial enrolls adults with solid tumors who are starting or have recently started immunotherapy. The goal is to see if a simple probiotic can reduce this risk.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

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