Gut feeling: probiotic shows promise for easing anxiety and depression
NCT ID NCT07353320
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a probiotic called Weizmannia coagulans BC99 can reduce symptoms of anxiety and depression in stressed adults. 79 people took either the probiotic or a placebo for 8 weeks. Researchers measured changes using standard depression and anxiety rating scales. The goal was to see if improving gut bacteria could boost mental health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Weizmannia coagulans BC99 (a probiotic)
What this could lead to
If it works, this could point toward a simple, natural supplement to help manage mild anxiety and depression.
What could go wrong
This is a small, early-stage trial with only 79 people. The effect may be small or no better than placebo, and results may not apply to everyone with anxiety or depression.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Henan University of Science and Technolog
Luoyang, Henan, 462000, China