Cure My Disease

Don't miss your cure!

 Log in / Sign up

Gut feeling: could a probiotic ease depression in young brains?

NCT ID NCT06898788

Recruiting now Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether a multi-strain probiotic called Visbiome can change brain activity and gut bacteria in people aged 15 to 24 with depression. Participants take either the probiotic or a placebo powder daily for several weeks. Researchers use brain scans and stool samples to see if the supplement affects mood-related brain circuits and the microbiome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an oral multi-strain probiotic called Visbiome
What this could lead to
If it works, this could point toward a new, side-effect-friendly way to help manage depression in young people by targeting the gut-brain connection.
What could go wrong
This is a very early, small study, so results may not be conclusive. Probiotics affect people differently, and any benefit might be modest or not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEPRESSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Depression depressive disorder dysthymic disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UCSF

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.