Gut check: lab study reveals how probiotics and meds shape your microbiome

NCT ID NCT06114303

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This lab study tested how two probiotic solutions and five types of drugs (antibiotics, acid reducers, painkillers, anxiety meds, and antidepressants) affect gut bacteria from human stool samples. The goal was to understand changes in bacterial activity and metabolism, not to treat any disease. The study involved 14 healthy adults and children, but was terminated early.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Mar 2024

Finished

Jun 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The mother/daughter " duos " participating in the study will be drawn from a panel of volunteers.

Ages

1 year to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Adult "Mother" population: * Women aged 25-40 years; * In good general health, i.e. no chronic pathology and not taking any medication at the time of inclusion and/or long-term treatment, * With a regular bowel movement frequency (at least once every 2 days) * BMI between 18.5 and 25 * Able and willing to participate in the research by complying with the protocol procedures * Not objecting to the collection and processing of their personal data Child "Daughter" population * Girl between 1 and 2 years old * In good general health, i.e. no chronic pathology and not taking any medication at the time of inclusion and/or on a long-term basis, * With a regular stool frequency (at least once every 2 days) * Whose mother does not object to the collection and processing of personal data Exclusion Criteria: Adult "Mother" population : * Pregnant or breastfeeding women, * Under antibiotic treatment, or having stopped it for less than a month. * Under dietary supplementation (prebiotics or probiotics) or having stopped it less than one month before * On antidepressants and/or anxiolytics in the month before inclusion * Taking a non-steroidal anti-inflammatory drug (NSAID) the month before inclusion. * On PPI, or having stopped it less than one month before. * Persons under court protection, * Person participating in another research study with an ongoing exclusion period, Child "Daughter" population: * Outside the WHO normal growth charts (weight for height) for girls aged 0-2 years (below the 3rd percentile or above the 97th percentile) * Undergoing antibiotic treatment, or having stopped it less than a month ago. * Having taken a non-steroidal anti-inflammatory drug (NSAID) in the month prior to inclusion. * On dietary supplements (prebiotics or probiotics) or having stopped them within the last month * Subjects participating in another research study with an ongoing exclusion period

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Conditions

The condition(s) this trial relates to.

Dysbiosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amandine FRY

    Dijon, 21000, France

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