Gut check: lab study reveals how probiotics and meds shape your microbiome
NCT ID NCT06114303
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This lab study tested how two probiotic solutions and five types of drugs (antibiotics, acid reducers, painkillers, anxiety meds, and antidepressants) affect gut bacteria from human stool samples. The goal was to understand changes in bacterial activity and metabolism, not to treat any disease. The study involved 14 healthy adults and children, but was terminated early.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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14 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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Jun 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The mother/daughter " duos " participating in the study will be drawn from a panel of volunteers.
- Ages
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1 year to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adult "Mother" population: * Women aged 25-40 years; * In good general health, i.e. no chronic pathology and not taking any medication at the time of inclusion and/or long-term treatment, * With a regular bowel movement frequency (at least once every 2 days) * BMI between 18.5 and 25 * Able and willing to participate in the research by complying with the protocol procedures * Not objecting to the collection and processing of their personal data Child "Daughter" population * Girl between 1 and 2 years old * In good general health, i.e. no chronic pathology and not taking any medication at the time of inclusion and/or on a long-term basis, * With a regular stool frequency (at least once every 2 days) * Whose mother does not object to the collection and processing of personal data Exclusion Criteria: Adult "Mother" population : * Pregnant or breastfeeding women, * Under antibiotic treatment, or having stopped it for less than a month. * Under dietary supplementation (prebiotics or probiotics) or having stopped it less than one month before * On antidepressants and/or anxiolytics in the month before inclusion * Taking a non-steroidal anti-inflammatory drug (NSAID) the month before inclusion. * On PPI, or having stopped it less than one month before. * Persons under court protection, * Person participating in another research study with an ongoing exclusion period, Child "Daughter" population: * Outside the WHO normal growth charts (weight for height) for girls aged 0-2 years (below the 3rd percentile or above the 97th percentile) * Undergoing antibiotic treatment, or having stopped it less than a month ago. * Having taken a non-steroidal anti-inflammatory drug (NSAID) in the month prior to inclusion. * On dietary supplements (prebiotics or probiotics) or having stopped them within the last month * Subjects participating in another research study with an ongoing exclusion period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amandine FRY
Dijon, 21000, France
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Other studies related to the condition(s) this trial covers.
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