New probiotic cocktail put to the test: safe or just hype?

NCT ID NCT07566884

Ongoing Symptom relief Sponsor: Pendulum Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This two-phase study is testing whether a novel probiotic supplement is safe and well-tolerated in healthy adults aged 18 to 65. Thirty participants will take either a high or standard dose of the probiotic daily for eight weeks. Researchers will track side effects, blood markers, and also explore effects on food cravings, digestion, and appetite-related hormones.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Three-strain probiotic (Clostridium butyricum, Akkermansia muciniphila, Bifidobacterium infantis) plus prebiotic chicory inulin
What this could lead to: If it works, this could point toward a safe probiotic supplement that helps manage food cravings and gut health.
What could go wrong: This is a small, early-stage safety study in healthy adults, so it won't prove any health benefits. The probiotic may cause digestive discomfort or other mild side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY ADULTS

Contacts and locations

Locations

Atlantia Clinical Trials

Cork, Ireland

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