Could a gout drug help people safely quit opioids?

NCT ID NCT04939623

First seen May 03, 2026 · Last updated May 16, 2026 · Updated 3 times

Summary

This study tests whether probenecid, a safe drug already used for gout, can reduce the unpleasant symptoms of opioid withdrawal in people with chronic pain who are voluntarily lowering their opioid dose. About 40 adults will receive either probenecid or a placebo to see if it helps them taper more comfortably. The goal is to provide a new, accessible option to support people struggling to reduce their opioid use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC PAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Richmond Road Diagnostic and Treatment Centre

    RECRUITING

    Calgary, Alberta, T2T 5C7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.