Old gout drug could help curb alcohol cravings, new trial suggests
NCT ID NCT07118618
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests whether probenecid, a drug currently used for gout, can reduce alcohol cravings and drinking in people with alcohol use disorder. Over 16 weeks, 120 participants will receive either probenecid or a placebo, and researchers will measure changes in craving and alcohol consumption. The goal is to see if this drug offers a new way to help manage alcohol use disorder.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probenecid (oral tablet, 2 grams daily)
What this could lead to
If it works, this could point toward a new treatment option to help people with alcohol use disorder reduce cravings and drinking.
What could go wrong
This is an early Phase 2 trial with only 120 people, so results may not apply to everyone. Probenecid can cause side effects like kidney issues or allergic reactions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brown University
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact Email: •••••@•••••