Targeted chemo delivery aims to boost pancreatic cancer surgery success
NCT ID NCT07477418
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether delivering the chemotherapy drug gemcitabine directly into the artery feeding the tumor can improve surgical outcomes for people with borderline resectable pancreatic cancer. Ten participants will receive standard chemo and radiation, followed by the targeted gemcitabine infusion before surgery. The main goal is to see if this approach is safe and feasible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Gemcitabine delivered via transarterial microperfusion (RenovoCath catheter)
- What this could lead to
- If successful, this approach could help more patients with borderline resectable pancreatic cancer have clear surgical margins, potentially improving survival.
- What could go wrong
- This is a very early, small trial (10 participants) focused on safety and feasibility. The added procedure carries risks like bleeding or infection, and it may not improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Vermont Medical Center
Burlington, Vermont, 05401, United States
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