New hope for rare blood cancer: aggressive combo therapy shows promise

NCT ID NCT02858999

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study tested a multi-step treatment plan for 40 patients under 70 with primary plasma cell leukemia, a rare and aggressive blood cancer. The approach included several rounds of different chemotherapy drugs, followed by one or two stem cell transplants (using the patient's own cells or a donor's), and then more chemo to keep the cancer from coming back. The goal was to see how long patients could live without the disease getting worse.

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Contacts and locations

Locations

  • AP-HP

    Paris, 75004, France

  • CH Dunkerque

    Dunkirk, 59385, France

  • CH Pays d'Aix

    Aix-en-Provence, 13616, France

  • CHRU Lille

    Lille, 59037, France

  • CHU Amiens

    Amiens, 80054, France

  • CHU Besançon

    Besançon, 25030, France

  • CHU Caen

    Caen, 14033, France

  • CHU Clermont Ferrand

    Clermont-Ferrand, 63003, France

  • CHU Dijon

    Dijon, 21034, France

  • CHU Nancy

    Nancy, 54035, France

  • CHU Nantes

    Nantes, 44093, France

  • CHU Nice

    Nice, 06003, France

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Rennes

    Rennes, 35033, France

  • CHU Strasbourg

    Strasbourg, 67091, France

  • CHU Toulouse

    Toulouse, 31059, France

  • CHU Tours

    Tours, 37044, France

  • Hospices Civils de Lyon

    Lyon, 69229, France

Conditions

Explore the condition pages connected to this study.