Could a new pill break up Alzheimer's brain clumps?
NCT ID NCT06182085
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests a new drug called PRI-002 in 304 people with mild memory problems or early Alzheimer's. The drug aims to break apart harmful protein clumps in the brain that are linked to Alzheimer's. Researchers want to see if it is safe and can slow down memory and thinking decline over 48 weeks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ALZHEIMER'S DISEASE, EARLY ONSET are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
A-Shine, s.r.o.
Pilsen, 30100, Czechia
-
AOU Policlinico Umberto I
Rome, 00161, Italy
-
ASST Spedali Civili di Brescia
Brescia, 25123, Italy
-
Brain Research Center Amsterdam B.V.
Amsterdam, 1081 GN, Netherlands
-
Brain Research Center Den Bosch B.V.
's-Hertogenbosch, 5223 LA, Netherlands
-
Brain Research Center Zwolle B.V.
Zwolle, 8025 AZ, Netherlands
-
CLINTRIAL, s.r.o.
Prague, 10000, Czechia
-
Charité - Universitätsmedizin
Berlin, 13125, Germany
-
Clinica Neurologica Dipartimento di Neuroscienze e Imaging (CAST)
Chieti, 66013, Italy
-
Euromedis Sp. z o.o., Centrum Medyczne EUROMEDIS
Szczecin, 70-111, Poland
-
FORBELI s.r.o.
Prague, 14800, Czechia
-
Fondazione IRCCS.Istituto Neurologico Carlo Besta
Milan, 20133, Italy
-
Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, 00168, Italy
-
Fundació ACE - Institut Català de Neurociències Aplicades
Barcelona, 08028, Spain
-
Hospital Clínico Universitario Virgen de la Arrixaca
El Palmar, Murcia, 30120, Spain
-
Hospital Universitario Doctor Peset
Valencia, 46017, Spain
-
Hospital Universitario Virgen Macarena,
Seville, 41003, Spain
-
Hospital Viamed Montecanal
Zaragoza, 50012, Spain
-
INEP Medical s.r.o.
Prague, 18600, Czechia
-
IRCCS Ospedale San Raffaele
Milan, 20132, Italy
-
ISPG - Institut für Studien zur Psychischen Gesundheit
Mannheim, 68165, Germany
-
Krakowska Akademia Neurologii Sp. z o.o., Centrum Neurologii Klinicznej
Krakow, 30-505, Poland
-
Neuro Health Centrum ltd.
Brno, 62800, Czechia
-
NeuroCor, ul. Medweciego 7/U12
Krakow, 31-870, Poland
-
Neuroprotect Sp. z o.o., Centrum Medyczne NeuroProtect
Warsaw, 01-684, Poland
-
Neuropsychiatrie s.r.o.
Prague, 16000, Czechia
-
NeuropsychiatrieHK, s.r.o.
Hradec Králové, 50341, Czechia
-
Ospedale Bellaria - IRCCS Istituto delle Scienze Neurologiche
Bologna, 40139, Italy
-
Ospedale Santa Maria della Misericordia
Perugia, 06129, Italy
-
Revit Sp. z o.o., Podlaskie Centrum Psychogeriatrii
Bialystok, 15-756, Poland
-
Technische Universität München
München, 81675, Germany
-
Uniklinik RWTH Aachen
Aachen, 52074, Germany
-
University Medical Center Rostock
Rostock, 18147, Germany
-
Universitätsklinikum Düsseldorf
Düsseldorf, 40225, Germany
-
Universitätsklinikum Magdeburg
Magdeburg, 39120, Germany
-
Universitätsklinikum Münster - Klinik für Allgemeine Neurologie
Münster, 48149, Germany
-
Universitätsklinikum Ulm
Ulm, 89081, Germany
-
Wielospecjalistyczne Centrum Medyczne "Ibismed" s.c.
Zabrze, 41-800, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could atomoxetine or metformin be the next Alzheimer's treatment?
- Can a zapping cap boost brainpower in Alzheimer's?
- Breathing your way to a sharper mind? new study tests combo therapy for memory loss
- Brain zaps show promise for memory in early Alzheimer's
- Could a spinal injection slow Alzheimer's? new trial underway
- Could a diabetes drug help detect Alzheimer's early?