Could a Patient's own blood and fat build a better breast after cancer surgery?

NCT ID NCT07658170

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a new approach to breast reconstruction after cancer surgery. Doctors take a patient's own fat and mix it with a substance made from their blood (platelet-rich fibrin) to create a 'lipobolus' that fills the gap left by tumor removal. The goal is to see how much of the graft survives after radiation therapy and whether the procedure is safe. The study involves 30 women with early-stage breast cancer who will be followed for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lipobolus (autologous fat mixed with platelet-rich fibrin and calcium chloride)

What this could lead to

If successful, this approach could offer a safer, more natural way to reconstruct breast shape immediately after cancer surgery, potentially improving cosmetic outcomes and patient satisfaction.

What could go wrong

This is a small, early-phase study with only 30 participants, so results may not apply to everyone. Risks include graft failure, infection, or interference with cancer treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Leningrad Regional Clinical Hospital

    RECRUITING

    Saint Petersburg, 188663, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••