Preworkout supplement may boost tired muscles, small study suggests
NCT ID NCT07217210
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a multi-ingredient preworkout supplement in 13 healthy men aged 19-29. Researchers measured leg muscle torque and electrical activity during a fatigue protocol. The goal was to see if the supplement improves muscle performance when tired.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Multi-ingredient preworkout supplement
- What this could lead to
- If it works, this could show that preworkout supplements boost muscle performance during fatigue, potentially aiding athletes.
- What could go wrong
- This is a very small, early study (13 healthy men) looking at short-term effects only. Results may not apply to others or predict long-term benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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13 people
The number who actually took part.
- Started
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Nov 2021
- Finished
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Apr 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 29 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male, 19-29 years of age, one year of resistance training experience Exclusion Criteria: * Subjects were eligible to participate if they did not report: 1) cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders; 2) use of any medications; 3) use of nutritional supplements; 4) habitual use of caffeine (≥ 1 caffeinated beverage per day); or 5) participation in another clinical trial or investigation of another nutritional product within 30 days of screening/enrollment.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Northern Illinois University
DeKalb, Illinois, 60115, United States
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