Penicillin shots tested to stop syphilis in pregnancy
NCT ID NCT07189208
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving penicillin shots to pregnant women at high risk for syphilis can prevent infection. Researchers in Rio de Janeiro will enroll 500 women and compare the shots to standard care. Participants receive monthly injections and tests during their third trimester.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
benzathine penicillin
What this could lead to
If it works, this could provide a simple way to prevent syphilis during pregnancy, reducing the risk of passing the infection to the baby.
What could go wrong
This is a Phase 2 trial, so it's still early. The drug may not prevent infection as hoped, and some participants may have allergic reactions or side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CONGENITAL SYPHILIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Centro de Referencia e Atenção Especializada a Saúde da Mulher (CRAESM)
NOT_YET_RECRUITINGDuque de Caxias, Rio de Janeiro, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Hospital Federal dos Servidores do Estado
RECRUITINGRio de Janeiro, Rio de Janeiro, Brazil
-
Policlínica Hospital Municipal Duque de Caxias
RECRUITINGDuque de Caxias, Rio de Janeiro, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Unidade Básica de Saúde José de Freitas
NOT_YET_RECRUITINGDuque de Caxias, Rio de Janeiro, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••