Simple staph test before surgery could slash infection risk
NCT ID NCT06378359
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether screening surgery outpatients for Staphylococcus aureus (staph) and giving them a 5-day decolonization treatment (nasal ointment, mouth rinse, and special soap) can prevent surgical site infections. About 250 adults scheduled for various surgeries will be split into four groups to compare different screening and treatment approaches. The goal is to find the safest, most effective way to eliminate staph before surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mupirocin, chlorhexidine gluconate, povidone-iodine, alcohol gel
- What this could lead to
- If successful, this could lead to a standard, cost-effective way to prevent surgical site infections by identifying and treating S. aureus carriers before surgery.
- What could go wrong
- This is a small pilot study (250 people) at one center, so results may not apply to everyone. The decolonization bundle may not work for all patients or may cause skin irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Minnesota Medical Center and Clinics
RECRUITINGMinneapolis, Minnesota, 55414, United States
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