Mouthwash may stop cancer treatment side effect in breast and lung cancer patients

NCT ID NCT06974604

Recruiting now Symptom relief Sponsor: Brown University Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 35 times

Summary

This study tests whether a steroid mouthwash (dexamethasone) can reduce mouth sores caused by the cancer drug datopotamab deruxtecan. About 60 adults with advanced breast or lung cancer will use the mouthwash four times a day for the first five days of each treatment cycle. The goal is to lower the rate of stomatitis (mouth inflammation) by 20% compared to historical data.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Rhode Island and the Miriam Hospitals (Brown University Health)
RECRUITING

Providence, Rhode Island, 02903/02906, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

BREAST NEOPLASMS BREAST NEOPLASMS LUNG NEOPLASMS

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.

HORMONE RECEPTOR-POSITIVE BREAST CANCER