Major trial to settle debate: which blood pressure drug saves kidneys during surgery?
NCT ID NCT06802224
First seen Mar 16, 2026 · Last updated May 22, 2026 · Updated 8 times
Summary
This study compares two standard drugs, norepinephrine and phenylephrine, used to treat low blood pressure during major surgery. The goal is to see which one better prevents kidney injury after the operation. About 18,000 adults having non-cardiac surgery lasting at least two hours will take part, with hospitals alternating which drug they use each month.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Henry Ford Health
RECRUITINGDetroit, Michigan, 48202, United States
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Maryland
RECRUITINGCollege Park, Maryland, 20742, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
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Wake Forest University School of Medicine
RECRUITINGWinston-Salem, North Carolina, 27101, United States
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