New antibiotic combo cuts surgical infections in colorectal patients

NCT ID NCT02618720

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding an oral antibiotic (ornidazole) the day before colorectal surgery to the standard IV antibiotic given at incision time could reduce surgical site infections within 30 days. Over 900 adults having elective colorectal surgery took part. The goal was to see if the combined approach works better than IV antibiotics alone.

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France