Steroid flash before colon surgery: a shot at fewer complications?

NCT ID NCT03437746

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving a single high dose of the steroid methylprednisolone just before colorectal surgery could lower the risk of serious complications, especially infections. The trial planned to enroll 78 adults having elective colorectal surgery, but it was terminated early, so the results are not conclusive. The idea was to calm the body's inflammatory response to surgery, which might help prevent infections and speed recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

methylprednisolone (a corticosteroid)

What this could lead to

If it worked, this could point toward a simple way to lower infection risk after colorectal surgery.

What could go wrong

This was a small, early pilot study that was terminated, so we don't have clear evidence it works. Steroids can also have side effects like increased infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Dijon Bourgogne

    Dijon, 21000, France