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Mesh may prevent hernias after surgery, but trial cut short

NCT ID NCT03912662

Terminated Prevention Sponsor: Medtronic - MITG Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a special mesh placed during abdominal surgery to prevent incisional hernias, which can occur in 10-50% of patients. The trial enrolled 32 adults undergoing elective midline laparotomy and tracked hernia development for 24 months using CT scans and exams. However, the study was terminated early, limiting what can be concluded.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ProGrip self-gripping polyester mesh
What this could lead to
If successful, this mesh could reduce the risk of incisional hernias after abdominal surgery, lowering the need for additional operations.
What could go wrong
The trial was terminated early with only 32 participants, so results are limited. The mesh may not work for everyone and carries risks like infection or pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INCISIONAL HERNIA

Contacts and locations

Locations

  • CHU Besançon

    Besançon, France

  • CHU Hopitaux de Rouen

    Rouen, France

  • CHU Lille

    Lille, France

  • CHU Strasbourg - Nouvel Hôpital Civil

    Strasbourg, 67000, France

  • CHU de Bordeaux

    Bordeaux, 33076, France

  • CHU de Bordeaux - Hôpital Haut-Lévêque

    Bordeaux, France

  • CHU de Nantes

    Nantes, 44000, France

  • CHU de Nîmes

    Nîmes, 30029, France

  • CHU de Rennes - Hôpital Pontchaillou

    Rennes, 35033, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69310, France

  • HCL Louis Pradel

    Lyon, France

More trials for these conditions

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