New drug tested to keep dialysis lifelines flowing

NCT ID NCT05027074

Completed Prevention Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study tested whether an experimental drug called MK-2060 could prevent dangerous blood clots from forming in the artificial grafts used for dialysis in people with kidney failure. Over 500 participants received either one of two doses of the drug or a placebo to see which worked better at delaying the first clot. The goal was to find a safe and effective dose to use in larger future studies.

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Contacts and locations

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Locations

AKDHC MEDICAL RESEARCH SERVICES, LLC-Maryvale ( Site 0723)

Phoenix, Arizona, 85035, United States
AKDHC Medical Research Services, LLC ( Site 0629)

Tucson, Arizona, 85741, United States
ASST Grande Ospedale Metropolitano Niguarda ( Site 0953)

Milan, 20162, Italy
ATTIKON GENERAL UNIVERSITY HOSPITAL-2nd Dep. of Int. Medicine. Research Unit & Diabetes Center ( Sit

Chaïdári, Attica, 124 62, Greece
Academic Medical Research Institute ( Site 0533)

Los Angeles, California, 90022, United States
Akademiska sjukhuset-Njurmottagningen ( Site 0453)

Uppsala, Uppsala County, 751 85, Sweden
Albert Einstein College of Medicine-Department of Medicine-Nephrology Einstein ( Site 0628)

The Bronx, New York, 10461, United States
CEREHA ( Site 0004)

Sarandí, Buenos Aires, B1872JBA, Argentina
California Institute Of Renal Research ( Site 0660)

Chula Vista, California, 91910, United States
California Institute Of Renal Research ( Site 0679)

El Centro, California, 92243, United States
California Institute of Renal Research ( Site 0566)

Escondido, California, 92025, United States
California Institute of Renal Research - Kearny Mesa ( Site 0678)

San Diego, California, 92111, United States
California Institute of Renal Research - La Mesa ( Site 0682)

La Mesa, California, 91941, United States
Capital District Renal Physicians ( Site 0633)

Albany, New York, 12209, United States
Capital Nephrology ( Site 0596)

Greenbelt, Maryland, 20770, United States
Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 0010)

Buenos Aires, Buenos Aires F.D., C1431FWO, Argentina
Citrus Dialysis Center ( Site 0609)

Covina, California, 91723, United States
Clinical Research Consultants, LLC ( Site 0542)

Kansas City, Missouri, 64111, United States
Clinical Research Strategies ( Site 0625)

Houston, Texas, 77090, United States
Clínica de Nefrología, Urología y Enfermedades Cardiovasculares ( Site 0001)

Santa Fe, 3000, Argentina
DaVita Anaheim West Dialysis-Davita Anaheim West Dialysis - Ismail ( Site 0562)

Anaheim, California, 92801, United States
DaVita Bakersfield Oak Street Dialysis-Clinical Research ( Site 0547)

Bakersfield, California, 93304, United States
DaVita Clinical Research ( Site 0502)

Minneapolis, Minnesota, 55404, United States
DaVita Clinical Research - Columbus ( Site 0532)

Columbus, Georgia, 31904, United States
DaVita Clinical Research - El Paso ( Site 0505)

El Paso, Texas, 79925, United States
DaVita Clinical Research - Hartford ( Site 0507)

Hartford, Connecticut, 06112, United States
DaVita Clinical Research - Houston ( Site 0508)

Houston, Texas, 77004, United States
DaVita Clinical Research - Middlebury ( Site 0511)

Middlebury, Connecticut, 06762, United States
DaVita Clinical Research - Milwaukee ( Site 0512)

Wauwatosa, Wisconsin, 53226, United States
DaVita Clinical Research - Norfolk ( Site 0513)

Norfolk, Virginia, 23502, United States
DaVita Clinical Research Germany GmbH ( Site 0901)

Düsseldorf, North Rhine-Westphalia, 40210, Germany
DaVita Clinical Researh ( Site 0501)

The Bronx, New York, 10461, United States
DaVita Crescent Heights Dialysis Center ( Site 0574)

Los Angeles, California, 90048, United States
DaVita East Georgia Dialysis Unit ( Site 0536)

Statesboro, Georgia, 30458, United States
DaVita Five Star Dialysis Center ( Site 0509)

Las Vegas, Nevada, 89128, United States
DaVita Glendale Heights ( Site 0604)

Glendale, California, 91201, United States
DaVita Kidney Center - East LA Plaza Dialysis ( Site 0548)

Los Angeles, California, 90033, United States
DaVita North Glendale ( Site 0552)

Glendale, California, 91206, United States
DaVita Van Nuys Dialysis ( Site 0538)

Van Nuys, California, 91405, United States
DaVita West Glendale Dialysis ( Site 0579)

Glendale, California, 91205, United States
Desert Cities Diaylsis-Clinical Research ( Site 0615)

Victorville, California, 92392, United States
Dialýza ( Site 0256)

Beroun, 266 01, Czechia
Durham Nephrology Associates ( Site 0655)

Durham, North Carolina, 27704, United States
Dyalisis Center - Clinic NephroCare Lumiar -Fresenius ( Site 0853)

Lisbon, Lisbon District, 1750-130, Portugal
East Carolina University-Department of Nephrology & Hypertension ( Site 0663)

Greenville, North Carolina, 27834, United States
Elixia Clinical Research Collaborative (CRC) - Southeast Florida ( Site 0728)

Hollywood, Florida, 33020, United States
Elixia at Clinical Renal Associates ( Site 0677)

Upland, Pennsylvania, 19013, United States
Elixia at Florida Kidney Physicians - Southeast ( Site 0602)

Fort Lauderdale, Florida, 33308, United States
FME Mansilla ( Site 0007)

Ciudad Autonoma de Buenos Aires, Buenos Aires, C1425BPM, Argentina
First Dialysis Services Bulgaria ( Site 0158)

Montana, 3400, Bulgaria
Floridian Clinical Research, LLC ( Site 0684)

Miami Lakes, Florida, 33016, United States
Fondazione Salvatore Maugeri clinica del lavoro ( Site 0955)

Pavia, 27100, Italy
Fresenius Clinical Trials Perdizes ( Site 0101)

São Paulo, São Paulo, 05024-030, Brazil
Fresenius Kidney Care - Charlotte ( Site 0686)

Charlotte, North Carolina, 28208, United States
Fresenius Kidney Care Bakersfield Northeast ( Site 0647)

Bakersfield, California, 93306, United States
Fresenius Kidney Care Brookhaven ( Site 0693)

Brookhaven, Mississippi, 39601, United States
Fresenius Kidney Care Meadows Field ( Site 0618)

Bakersfield, California, 93308, United States
Fresenius Kidney Care Newhope Fountain Valley ( Site 0617)

Fountain Valley, California, 92708, United States
Fresenius Medical Care ( Site 0253)

Pardubice, 532 03, Czechia
Fresenius Medical Care - Dialyzační středisko ( Site 0254)

Prague, Praha 4, 142 00, Czechia
Fresenius Medical Care - Moron ( Site 0008)

Morón, Buenos Aires, B1708DPO, Argentina
Fresenius Medical Care - NephroCare Almada ( Site 0854)

Corroios, Lisbon District, 2855-227, Portugal
Fresenius Medical Care - NephroCare Amadora ( Site 0851)

Amadora, Lisbon District, 2700-391, Portugal
Fresenius Medical Care - NephroCare Covilha ( Site 0852)

Covilha, Castelo Branco District, 6200-000, Portugal
Fresenius Medical Care - Nephrocare Portimao ( Site 0855)

Portimão, Faro District, 8500-311, Portugal
Fresenius Medical Care - San Fernando ( Site 0013)

San Fernando, Buenos Aires, 1646, Argentina
Fresenius Medical Care Ciudad Evita ( Site 0006)

Buenos Aires, B1778IFA, Argentina
Fresenius Medical Care Humacao ( Site 0354)

Humacao, 00971, Puerto Rico
Fresenius Nephrocare - Brașov ( Site 0409)

Brașov, Brăila County, 500152, Romania
Fresenius Nephrocare - Bucharest ( Site 0408)

Bucharest, București, 013217, Romania
Fresenius Nephrocare - Cluj-Napoca ( Site 0410)

Cluj-Napoca, Cluj, 400528, Romania
Fresenius Nephrocare - Iași ( Site 0406)

Iași, Iaşi, 700523, Romania
Fundação Faculdade Regional de Medicina de São José do Rio Preto-Centro Integrado de Pesquisa ( Site

São José do Rio Preto, São Paulo, 15090000, Brazil
G. Papanikolaou General Hospital-Nephrology Department ( Site 1052)

Thessaloniki, 570 10, Greece
Gamma Medical Research ( Site 0688)

McAllen, Texas, 78503, United States
Genesis Clinical Research, LLC ( Site 0585)

Tampa, Florida, 33603, United States
Genesis Clinical Research, LLC ( Site 0594)

Tampa, Florida, 33603, United States
Genesis Clinical Research, LLC ( Site 0680)

Tampa, Florida, 33603, United States
Hemomed ( Site 0159)

Sofia, 1618, Bulgaria
Henry Ford Hospital-Nephrology and Hypertension ( Site 0694)

Detroit, Michigan, 48202, United States
Horizon Research Group ( Site 0578)

Coral Gables, Florida, 33134, United States
Horizon Research Group ( Site 0581)

Coral Gables, Florida, 33134, United States
Hospital do Rim e Hipertensão ( Site 0106)

São Paulo, 04038-002, Brazil
Ippokrateio General Hospital of Thessaloniki ( Site 1053)

Thessaloniki, Central Macedonia, 546 42, Greece
Karolinska Universitetssjukhuset Huddinge-ME Njurmedicin ( Site 0451)

Stockholm, Stockholm County, 141 86, Sweden
Kidney and Hypertension Center ( Site 0571)

Roseburg, Oregon, 97471, United States
Knoxville Kidney Center ( Site 0689)

Knoxville, Tennessee, 37923, United States
La Puente Dialysis Center ( Site 0610)

La Puente, California, 91744, United States
Limited Liability Company -Nefroline-Novosibirsk ( Site 0810)

Novosibirsk, Novosibirsk Oblast, 630064, Russia
MHAT Dobrich-Department for dialysis treatment ( Site 0161)

Dobrich, 9300, Bulgaria
Multiprofile Hospital for Active Treatment - "Dr. Cherven Bryag"-Department of dialysis treatment (

Cherven Bryag, Lovech, 5980, Bulgaria
Nephrology Consultants ( Site 0681)

Huntsville, Alabama, 35805, United States
Nephrology Specialists - Merrillville ( Site 0537)

Merrillville, Indiana, 46410, United States
Nephrology Specialists - Michigan City ( Site 0541)

Michigan City, Indiana, 46360, United States
North America Research Institute ( Site 0587)

Lynwood, California, 90262, United States
North America Research Institute ( Site 0611)

San Dimas, California, 91773, United States
North America Research Institute ( Site 0612)

Lynwood, California, 90262, United States
Northeast Clinical Research Center ( Site 0653)

Bethlehem, Pennsylvania, 18017, United States
Omega Research Orlando ( Site 0645)

Orlando, Florida, 32808, United States
P.O. San Carlo Borromeo- ASST SANTI PAOLO E CARLO ( Site 0954)

Milan, Milano, 20153, Italy
Pines Clinical Research ( Site 0605)

Hollywood, Florida, 33024, United States
Renal Disease Research Institute ( Site 0621)

Dallas, Texas, 75235, United States
Renal Medicine Associates ( Site 0690)

Albuquerque, New Mexico, 87109, United States
Renal Physicians of Georgia ( Site 0577)

Macon, Georgia, 31217, United States
Research Physicians Network Alliance ( Site 0563)

Boca Raton, Florida, 33431, United States
Ridgewood Dialysis Center ( Site 0725)

Ridgewood, New York, 11385, United States
Skånes Universitetssjukhus Malmö ( Site 0454)

Malmo, Skåne County, 205 02, Sweden
Somnos Clinical Research ( Site 0669)

Lincoln, Nebraska, 68505, United States
South Carolina Nephrology & Hypertension Center-Research ( Site 0672)

Orangeburg, South Carolina, 29118, United States
South Florida Research Institute ( Site 0656)

Fort Lauderdale, Florida, 33313, United States
Southwest Houston Research ( Site 0649)

Houston, Texas, 77099, United States
St. Clair Nephrology Research - Roseville ( Site 0597)

Roseville, Michigan, 48066, United States
Texas Institute for Kidney and Endocrine Disorders ( Site 0626)

Lufkin, Texas, 75904, United States
Toronto General Hospital ( Site 1002)

Toronto, Ontario, M5G 2C4, Canada
UMBAL Plovdiv AD-Deparment of Hemodialysis ( Site 0162)

Plovdiv, 4003, Bulgaria
Unipharm LLC ( Site 0804)

Krasnogorsk, Moscow Oblast, 143403, Russia
University Of Alberta Hospital ( Site 1001)

Edmonton, Alberta, T6G 2B7, Canada
University of Chicago Medical Center-Medicine - Section of Nephrology ( Site 0595)

Chicago, Illinois, 60637, United States
Valley Renal Medical Group Research-Clinical Research ( Site 0651)

Northridge, California, 91343, United States
Western Health-Sunshine & Footscray Hospitals-Renal Services ( Site 0054)

St Albans, Victoria, 3021, Australia

Conditions

Explore the condition pages connected to this study.

END STAGE RENAL DISEASE END-STAGE KIDNEY DISEASE KIDNEY FAILURE, CHRONIC