New antibody drugs aim to stop Catheter-Related blood clots

NCT ID NCT06299111

Summary

This study is testing two new antibody drugs, REGN9933 and REGN7508, to see if they can safely prevent dangerous blood clots in adults who need a PICC line catheter. About 195 participants will receive either one of the study drugs or a placebo. The main goals are to see if the drugs reduce clot risk and to monitor for any side effects.

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Contacts and locations

Locations

  • Arensia Exploratory Medicine Clinic at Country Hospital Cluj-Napoca

    Cluj-Napoca, 400006, Romania

  • Arensia Research Clinic

    Bucharest, 011658, Romania

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cardiff and Vale University Health Board - University Hospital Wales

    Cardiff, Wales, CF14 4XW, United Kingdom

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Hadassah University Medical Center

    Jerusalem, 91120, Israel

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Juravinski Hospital

    Hamilton, Ontario, L8V 1C3, Canada

  • Lakeridge Health

    Oshawa, Ontario, L1G 2B9, Canada

  • Lanadio Medical Center

    Netanya, 4244916, Israel

  • London Health Sciences Centre

    London, Ontario, N6A 4L6, Canada

  • Memorial Sloan Kettering

    New York, New York, 10065, United States

  • Mount Sinai Medical Center

    New York, New York, 10029, United States

  • Rabin Medical Center

    Petah Tikva, 49100, Israel

  • Shaare Zedek Medical Center

    Jerusalem, Jerusalem, 9103102, Israel

  • Sheba Medical Center

    Ramat Gan, 5265601, Israel

  • Soroka University Medical Center

    Beersheba, Southern District, 84101, Israel

  • Sveta Sofia Hospital

    Sofia, 1000, Bulgaria

  • Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, 64239, Israel

  • The Newcastle Upon Tyne Hospitals NHS Foundation Trust

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • University Health Network

    Toronto, Ontario, M5G 2M9, Canada

  • University hospital Southampton

    Southampton, Hampshire, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.