Heart attack prevention: should doctors stent dangerous plaques early?
NCT ID NCT07569692
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an early, aggressive approach—using a catheter to open and stent high-risk plaques seen on a CT scan—plus medication is better than medication alone for preventing heart problems. About 2,500 people with coronary artery disease will be randomly assigned to one of the two strategies. The goal is to see which approach reduces deaths, heart attacks, and hospitalizations over three years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
invasive coronary angiography with preventive percutaneous coronary intervention (PCI) plus optimal medical therapy
What this could lead to
If successful, this could show that early, preventive stenting of high-risk plaques reduces heart attacks and hospitalizations compared to medication alone.
What could go wrong
This is a large trial but has not yet started recruiting. The invasive procedure carries risks like bleeding or vessel damage, and the benefit over medication alone is unproven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asan Medical Center
Seoul, South Korea