New TB drug tested in kids: a step toward safer treatment

NCT ID NCT05586230

First seen Apr 24, 2026 · Last updated May 23, 2026 · Updated 5 times

Summary

This study looked at how a single dose of the drug pretomanid works in 32 children with rifampicin-resistant tuberculosis (TB), some of whom also had HIV. Researchers measured drug levels in the blood and checked for side effects. The goal was to gather information to help design better TB treatments for children.

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Contacts and locations

Locations

  • Site 31441, BJMC CRS

    Pune, India

  • Site 31790, Desmond Tutu TB Centre (DTTC) CRS

    Cape Town, South Africa

  • Site 31929, Sizwe CRS

    Johannesburg, South Africa

  • Site 31976, PHRU Matlosana CRS

    Klerksdorp, North West, 2574, South Africa

  • Site 5071, Instituto de Puericultura e Pediatria Martagao Gesteira CRS

    Rio de Janeiro, Brazil

  • Site 5115, Siriraj Hospital, Mahidol University NICHD CRS

    Bangkok Noi, Thailand

Conditions

Explore the condition pages connected to this study.