Lupus kidney trial aims for faster remission with drug cocktail
NCT ID NCT07611214
First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times
Summary
This study tests whether adding LUPKYNIS to standard biologic therapies (belimumab, obinutuzumab, or anifrolumab) can quickly improve kidney function in people with lupus nephritis. About 150 adults with biopsy-confirmed lupus kidney disease will receive the combination treatment. The main goal is to see how many achieve complete kidney response within 24 weeks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Accurate Clinical Research, Inc.
RECRUITINGLake Charles, Louisiana, 70605, United States
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Arthritis and Osteoporosis Consultants of the Carolinas
RECRUITINGCharlotte, North Carolina, 28202, United States
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Arthritis and Rheumatism Associates
RECRUITINGRockville, Maryland, 20850, United States
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Buffalo Rheumatology and Medicine, PLLC
RECRUITINGOrchard Park, New York, 14217, United States
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CTR Oakwater
RECRUITINGOrlando, Florida, 32806, United States
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Dunes Clinical Research
RECRUITINGDakota Dunes, South Dakota, 57049, United States
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Integrative Rheumatology of South Texas
RECRUITINGHarlingen, Texas, 78550, United States
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Joint and Muscle Research Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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Kansas City Physician Partners
RECRUITINGKansas City, Missouri, 64151, United States
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Liberty Research Center
RECRUITINGDallas, Texas, 75230, United States
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Life Clinical Trials
RECRUITINGMargate, Florida, 33063, United States
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Nephrology Leaders and Associates, PLLC
RECRUITINGVan Vleck, Texas, 77482, United States
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Northwest Houston Arthritis Center
RECRUITINGHouston, Texas, 77090, United States
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Novel Research LLC
RECRUITINGBellaire, Texas, 77401, United States
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Parris and Associates Rheumatology
RECRUITINGLawrenceville, Georgia, 30044, United States
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Purushotham & Akther Kotha MD, Inc.
RECRUITINGLa Mesa, California, 91942, United States
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Rheumatic Disease Associates, Ltd.
RECRUITINGWillow Grove, Pennsylvania, 19090, United States
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Sahni Rheumatology & Therapy
RECRUITINGWest Long Branch, New Jersey, 07764, United States
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Swati Shah MD Rheumatology, LLC
RECRUITINGJacksonville, Florida, 32257, United States
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Texas Arthritis Center
RECRUITINGEl Paso, Texas, 79902, United States
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Texas Rheumatology Research Institute, LLC
RECRUITINGPlano, Texas, 75024, United States
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Texas Tech University Health Science Center
RECRUITINGLubbock, Texas, 79430, United States
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University of Nevada Las Vegas
RECRUITINGLas Vegas, Nevada, 89102, United States
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Valerius Medical Group & Research Center of Greater Long Beach, Inc.
RECRUITINGLos Alamitos, California, 90720, United States
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Vida Clinical Research
RECRUITINGKissimmee, Florida, 34741, United States
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West Tennessee Research Institute
RECRUITINGJackson, Tennessee, 38305, United States
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Western Nephrology & Metabolic Bone Disease, PC
RECRUITINGArvada, Colorado, 80002, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A simple blood test may reveal kidney damage in lupus — no biopsy needed?
- Can a Three-Drug combo quiet lupus kidney flares?
- Can a single infusion tame tough lupus?
- Can a smartphone app bridge the lupus care gap for women of color?
- Can a single drug calm lupus kidney disease without a cocktail of meds?
- Cancer drug shows promise for lupus kidney disease