Tiny tube could tame glaucoma without daily drops
NCT ID NCT07235592
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a small implant called the PRESERFLO™ MicroShunt XI in people with primary open-angle glaucoma whose eye pressure remains high despite maximum medication. The implant is placed under the eye's surface to drain fluid and lower pressure. Researchers will check if it safely reduces pressure by at least 20% and keeps it in a healthy range for 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PRESERFLO™ MicroShunt XI implant (a tiny tube placed in the eye to drain fluid and lower pressure)
What this could lead to
If it works, this could offer a safe, long-term way to control eye pressure in glaucoma patients, possibly reducing the need for daily eye drops.
What could go wrong
This is a mid-stage study with only 112 participants, so results may not apply to everyone. The implant is a surgical device, so risks include infection, scarring, or the device not working as expected.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PRIMARY OPEN ANGLE GLAUCOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
AKH Wien
NOT_YET_RECRUITINGVienna, Austria
Contact
-
Glaucoma Clinic, UZ Leuven
NOT_YET_RECRUITINGLeuven, Belgium
Contact
-
Guy's and St. Thomas' NHS Foundation Trust
RECRUITINGLondon, United Kingdom
Contact
-
Hospital Clinico San Carlos
NOT_YET_RECRUITINGSan Carlos, Spain
Contact
-
Internationale Innovative Opthalmochirurgie GbR
NOT_YET_RECRUITINGDüsseldorf, Germany
Contact
-
Irccs Fondazione G. B. Bietti
NOT_YET_RECRUITINGRome, Italy
Contact
-
Moorfields Eye Hospital NHS Foundation Trust
NOT_YET_RECRUITINGLondon, United Kingdom
Contact
-
Policlinico Universitario Molinette
NOT_YET_RECRUITINGTurin, Italy
Contact
-
ULS Santa Maria, Lisboa
NOT_YET_RECRUITINGLisbon, Portugal
Contact
-
Universiteitskliniek voor Oogheelkunde Maastricht
NOT_YET_RECRUITINGMaastricht, Netherlands
Contact
-
Universitätsklinikum Tübingen, Department für Augenheilkunde
NOT_YET_RECRUITINGTübingen, Germany
Contact