Radiation before surgery: a new hope for breast cancer patients?

NCT ID NCT05464667

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests giving radiation therapy before surgery to women aged 50+ with early-stage, hormone-positive breast cancer. The goal is to find the safest radiation dose and see how the tumor responds. Only 15 participants are enrolled, making this a very early-stage trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy

What this could lead to

If successful, this could lead to a new treatment option that allows doctors to see how the tumor responds to radiation before surgery, potentially improving outcomes.

What could go wrong

This is a very early, small trial (15 people) focused on finding the safest dose, not on curing cancer. It may not work for all patients, and side effects like skin irritation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UPMC Magee Womens Hospital - Radiation Oncology

    Pittsburgh, Pennsylvania, 15213, United States