Radiation before surgery: a new hope for breast cancer patients?

NCT ID NCT05464667

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests giving radiation therapy before surgery to women aged 50+ with early-stage, hormone-positive breast cancer. The goal is to find the safest radiation dose and see how the tumor responds. Only 15 participants are enrolled, making this a very early-stage trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiation therapy
What this could lead to
If successful, this could lead to a new treatment option that allows doctors to see how the tumor responds to radiation before surgery, potentially improving outcomes.
What could go wrong
This is a very early, small trial (15 people) focused on finding the safest dose, not on curing cancer. It may not work for all patients, and side effects like skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UPMC Magee Womens Hospital - Radiation Oncology

    Pittsburgh, Pennsylvania, 15213, United States

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Other studies related to the condition(s) this trial covers.