Could a simple iodine solution make thyroid surgery safer?

NCT ID NCT04856488

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving Lugol's solution before removing the thyroid gland can lower the chance of two common surgery complications: low calcium levels from damaged parathyroid glands and vocal cord weakness from nerve injury. About 182 adults with overactive thyroid from Graves' disease or toxic nodular goiter will take part. The goal is to make surgery safer and reduce the need for long-term calcium or vitamin D supplements.

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Conditions

The condition(s) this trial relates to.

Graves disease hyperthyroidism toxic multinodular goitre

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Endocrinology, Karolinska University Hospital

    RECRUITING

    Solna, Stockholm County, 17176, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••