Can a 4-Week Pre-Surgery boost cut complications in GI cancer surgery?

NCT ID NCT06404489

Ongoing Symptom relief Sponsor: Università Vita-Salute San Raffaele Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 4-week program of exercise, nutrition advice, and stress management before major gastrointestinal cancer surgery can reduce serious complications within 30 days after the operation. About 400 adult patients scheduled for elective GI cancer surgery will take part. The program is tailored to each patient's needs and aims to improve their physical and mental readiness for surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Multimodal prehabilitation program (exercise, nutrition optimization, and distress-coping techniques)
What this could lead to: If it works, this could reduce serious complications and shorten hospital stays for people undergoing major gastrointestinal cancer surgery.
What could go wrong: This is a single-center study with 400 participants, and the program is tailored individually, so results may not apply to all patients or hospitals. The intervention is behavioral, so adherence and effectiveness can vary.

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Conditions

The condition(s) this trial relates to.

digestive system cancer Motor Activity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR SURGERY ONCOLOGICAL PATIENTS

Contacts and locations

Locations

Azienda Ospedaliera Universitaria

Cagliari, Sardinia, Italy
IRCCS San Raffaele Scientific Institute

Milan, 20132, Italy

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